Theoretical models of sheep BSE reveal possibilities
نویسندگان
چکیده
منابع مشابه
Sheep and Goat BSE Propagate More Efficiently than Cattle BSE in Human PrP Transgenic Mice
A new variant of Creutzfeldt Jacob Disease (vCJD) was identified in humans and linked to the consumption of Bovine Spongiform Encephalopathy (BSE)-infected meat products. Recycling of ruminant tissue in meat and bone meal (MBM) has been proposed as origin of the BSE epidemic. During this epidemic, sheep and goats have been exposed to BSE-contaminated MBM. It is well known that sheep can be expe...
متن کاملPossibilities to manage the BSE epidemic: cohort culling versus herd culling--experiences in Switzerland.
Bovine spongiform encephalopathy (BSE), a disease of cattle first reported in 1986 in the UK [1], has been found in the cattle populations of most European countries. To date, Japan, Israel and Canada are the only nonEuropean countries where BSE has been reported in indigenous cattle [2]. Given all available evidence, the BSE agent is not transmitted horizontally between cattle; rather it is pr...
متن کاملRapid and discriminatory diagnosis of scrapie and BSE in retro-pharyngeal lymph nodes of sheep
BACKGROUND Diagnosis based on prion detection in lymph nodes of sheep and goats can improve active surveillance for scrapie and, if it were circulating, for bovine spongiform encephalopathy (BSE). With sizes that allow repetitive testing and a location that is easily accessible at slaughter, retropharyngeal lymph nodes (RLN) are considered suitable organs for testing. Western blotting (WB) of b...
متن کاملPrP(d) accumulation in organs of ARQ/ARQ sheep experimentally infected with BSE by peripheral routes.
To study the pathogenesis of bovine spongiform encephalopathy infection in small ruminants, two Lacaune sheep with the AA136RR154QQ171 and one with the AA136RR154RR171 genotype for the prion protein, were inoculated with a brain homogenate from a French cattle BSE case by peripheral routes. Sheep with the ARQ/ARQ genotype are considered as susceptible to prion diseases contrary to those with th...
متن کاملPossibilities for Formal Models of Smart Environments
This paper is devoted to a recently running project descript ion with a purpose to get some necessary feedback from the AmI community as to the project ambitions. The project intends to study possibilities of several formal approaches towards modeling intelligent environments based on principles of ambient intelligence. The main goal is in contributing towards theoretical foundations of ambient...
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ژورنال
عنوان ژورنال: Nature
سال: 2002
ISSN: 0028-0836,1476-4687
DOI: 10.1038/415115a